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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK1
All Species:
22.73
Human Site:
T236
Identified Species:
45.45
UniProt:
O15075
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15075
NP_004725.1
740
82224
T236
G
V
V
K
R
L
Y
T
L
D
G
K
Q
V
M
Chimpanzee
Pan troglodytes
XP_522657
872
96662
T379
G
V
V
K
R
L
Y
T
L
D
G
K
Q
V
M
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
F260
V
T
C
L
Q
D
F
F
G
D
D
D
V
F
I
Dog
Lupus familis
XP_849124
740
82175
T236
G
V
V
K
R
L
Y
T
L
D
G
K
Q
V
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLM8
756
84135
T236
G
V
V
K
R
L
Y
T
L
D
G
K
Q
V
M
Rat
Rattus norvegicus
Q5MPA9
767
83998
F259
V
T
C
L
Q
D
F
F
G
D
D
D
V
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511397
792
88039
T297
G
V
V
K
R
L
Y
T
L
D
G
K
Q
V
M
Chicken
Gallus gallus
XP_417099
1048
115422
T542
G
V
V
K
R
L
Y
T
L
D
G
K
Q
V
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q501V0
422
47914
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI7
748
82953
N235
S
Y
V
C
S
C
N
N
E
N
F
K
K
V
E
Honey Bee
Apis mellifera
XP_394386
670
74883
H206
R
N
A
P
S
L
E
H
A
L
E
A
I
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
R198
I
K
S
G
A
K
P
R
K
A
V
R
I
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
65.3
99.8
N.A.
96.4
65.3
N.A.
86.2
63.7
N.A.
24.7
N.A.
29.8
41
N.A.
52.3
Protein Similarity:
100
80.1
77.5
99.8
N.A.
97.3
77.8
N.A.
88
64.9
N.A.
35
N.A.
47.5
57.9
N.A.
65.9
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
100
100
N.A.
0
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
26.6
N.A.
100
100
N.A.
0
N.A.
33.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
9
9
0
9
0
0
0
% A
% Cys:
0
0
17
9
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
17
0
0
0
67
17
17
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
17
% E
% Phe:
0
0
0
0
0
0
17
17
0
0
9
0
0
17
0
% F
% Gly:
50
0
0
9
0
0
0
0
17
0
50
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
17
0
17
% I
% Lys:
0
9
0
50
0
9
0
0
9
0
0
59
9
0
0
% K
% Leu:
0
0
0
17
0
59
0
0
50
9
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% M
% Asn:
0
9
0
0
0
0
9
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
0
50
0
0
% Q
% Arg:
9
0
0
0
50
0
0
9
0
0
0
9
0
0
0
% R
% Ser:
9
0
9
0
17
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
17
0
0
0
0
0
50
0
0
0
0
0
9
0
% T
% Val:
17
50
59
0
0
0
0
0
0
0
9
0
17
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _